Details of the Target
General Information of Target
| Target ID | LDTP01615 | |||||
|---|---|---|---|---|---|---|
| Target Name | Homeobox protein SIX6 (SIX6) | |||||
| Gene Name | SIX6 | |||||
| Gene ID | 4990 | |||||
| Synonyms |
OPTX2; SIX9; Homeobox protein SIX6; Homeodomain protein OPTX2; Optic homeobox 2; Sine oculis homeobox homolog 6 |
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| 3D Structure | ||||||
| Sequence |
MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIV
AFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFP LPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRR QRDRAAAAKNRLQQQVLSQGSGRALRAEGDGTPEVLGVATSPAASLSSKAATSAISITSS DSECDI |
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| Target Bioclass |
Transcription factor
|
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| Family |
SIX/Sine oculis homeobox family
|
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| Subcellular location |
Nucleus
|
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| Function | May be involved in eye development. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C44(37.04) | LDD0209 | [1] | |
|
4-Iodoacetamidophenylacetylene Probe Info |
 |
N.A. | LDD0038 | [2] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0036 | [2] | |
|
Lodoacetamide azide Probe Info |
 |
N.A. | LDD0037 | [2] | |
|
Compound 10 Probe Info |
 |
N.A. | LDD2216 | [3] | |
|
Compound 11 Probe Info |
 |
N.A. | LDD2213 | [3] | |
Competitor(s) Related to This Target
References