Details of the Target
General Information of Target
| Target ID | LDTP01603 | |||||
|---|---|---|---|---|---|---|
| Target Name | Apolipoprotein M (APOM) | |||||
| Gene Name | APOM | |||||
| Gene ID | 55937 | |||||
| Synonyms |
G3A; NG20; Apolipoprotein M; Apo-M; ApoM; Protein G3a |
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| 3D Structure | ||||||
| Sequence |
MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEEL
ATFDPVDNIVFNMAAGSAPMQLHLRATIRMKDGLCVPRKWIYHLTEGSTDLRTEGRPDMK TELFSSSCPGGIMLNETGQGYQRFLLYNRSPHPPEKCVEEFKSLTSCLDSKAFLLTPRNQ EACELSNN |
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| Target Bioclass |
Other
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| Family |
Calycin superfamily, Lipocalin family
|
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| Subcellular location |
Secreted
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| Function | Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| MOLT4 | Deletion: p.P65LfsTer26 SNV: p.C167S;p.L174Ter |
IA-alkyne Probe Info | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
BTD Probe Info |
 |
C95(0.94) | LDD2140 | [1] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0167 | [2] | |
Competitor(s) Related to This Target
The Interaction Atlas With This Target
References