Details of the Target
General Information of Target
| Target ID | LDTP01404 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cystatin-F (CST7) |
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| Gene Name | CST7 | |||||
| Gene ID | 8530 | |||||
| Synonyms |
Cystatin-F; Cystatin-7; Cystatin-like metastasis-associated protein; CMAP; Leukocystatin |
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| 3D Structure | ||||||
| Sequence |
MRAAGTLLAFCCLVLSTTGGPSPDTCSQDLNSRVKPGFPKTIKTNDPGVLQAARYSVEKF
NNCTNDMFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKKNQHLRLDDCDFQTNHTLKQ TLSCYSEVWVVPWLQHFEVPVLRCH |
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| Target Bioclass |
Other
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| Family |
Cystatin family
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| Subcellular location |
Secreted
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| Function | Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
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C63(1.51) | LDD2412 | [1] | |
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IA-alkyne Probe Info |
 |
N.A. | LDD0036 | [2] | |
Competitor(s) Related to This Target
References