Details of the Target

General Information of Target

Target ID LDTP01282
Target Name Cancer/testis antigen 2 (CTAG2)
Gene Name CTAG2
Gene ID 30848
Synonyms
ESO2; LAGE1; Cancer/testis antigen 2; CT2; Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 6.2; CT6.2; L antigen family member 1; LAGE-1
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MQAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGAGAARASGPRGGA
PRGPHGGAASAQDGRCPCGARRPDSRLLELHITMPFSSPMEAELVRRILSRDAAPLPRPG
AVLKDFTVSGNLLFMSVRDQDREGAGRMRVVGWGLGSASPEGQKARDLRTPKHKVSEQRP
GTPGPPPPEGAQGDGCRGVAFNVMFSAPHI
Target Bioclass
Other
Family
CTAG/PCC1 family
Uniprot ID
O75638
Ensemble ID
ENST00000247306.4
HGNC ID
HGNC:2492

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C196(0.00); C76(0.00)  LDD0147  [1]
TFBX
 Probe Info  		N.A.  LDD0148  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Desumoylating isopeptidase 1 (DESI1) DeSI family Q6ICB0
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) CAMK Ser/Thr protein kinase family P54646
tRNA-splicing endonuclease subunit Sen2 (TSEN2) TRNA-intron endonuclease family Q8NCE0
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein OTX1 (OTX1) Paired homeobox family P32242
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Thyroid receptor-interacting protein 6 (TRIP6) Zyxin/ajuba family Q15654
Axin-2 (AXIN2) . Q9Y2T1
Sperm mitochondrial-associated cysteine-rich protein (SMCP) . P49901
Ubiquilin-1 (UBQLN1) . Q9UMX0

References

1 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255