Details of the Target
General Information of Target
| Target ID | LDTP01242 | |||||
|---|---|---|---|---|---|---|
| Target Name | Heat shock factor-binding protein 1 (HSBP1) | |||||
| Gene Name | HSBP1 | |||||
| Gene ID | 3281 | |||||
| Synonyms |
HSF1BP; Heat shock factor-binding protein 1; Nasopharyngeal carcinoma-associated antigen 13; NPC-A-13 |
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| 3D Structure | ||||||
| Sequence |
MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAG
VEELESENKIPATQKS |
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| Target Bioclass |
Other
|
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| Family |
HSBP1 family
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| Subcellular location |
Nucleus
|
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| Function | Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
STPyne Probe Info |
 |
K26(7.35) | LDD2217 | [1] | |