Details of the Target

General Information of Target

Target ID LDTP01013
Target Name Tetraspanin-1 (TSPAN1)
Gene Name TSPAN1
Gene ID 10103
Synonyms
Tetraspanin-1; Tspan-1; Tetraspan NET-1; Tetraspanin TM4-C
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL
IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL
LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT
NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL
Q
Target Bioclass
Other
Family
Tetraspanin (TM4SF) family
Subcellular location
Lysosome membrane
Uniprot ID
O60635
Ensemble ID
ENST00000372003.6
HGNC ID
HGNC:20657

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0162  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Thiamine transporter 1 (SLC19A2) Reduced folate carrier (RFC) transporter (TC 2.A.48) family O60779
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription factor A, mitochondrial (TFAM) . Q00059
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transmembrane protein 80 (TMEM80) . Q96HE8

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060