Details of the Target

General Information of Target

Target ID LDTP00981
Target Name Myelin protein zero-like protein 2 (MPZL2)
Gene Name MPZL2
Gene ID 10205
Synonyms
EVA; EVA1; Myelin protein zero-like protein 2; Epithelial V-like antigen 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALT
VTWNFRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGT
YTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIGSACALMIIIVIVVVLFQHYRK
KRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD
Target Bioclass
Immunoglobulin
Family
Myelin P0 protein family
Subcellular location
Membrane
Function Mediates homophilic cell-cell adhesion.
Uniprot ID
O60487
Ensemble ID
ENST00000278937.7
HGNC ID
HGNC:3496

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
YN-1
 Probe Info  		100.00  LDD0444  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Myelin protein zero-like protein 3 (MPZL3) Myelin P0 protein family Q6UWV2

References

1 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.