Details of the Target
General Information of Target
| Target ID | LDTP00340 | |||||
|---|---|---|---|---|---|---|
| Target Name | Fructose-1,6-bisphosphatase isozyme 2 (FBP2) | |||||
| Gene Name | FBP2 | |||||
| Gene ID | 8789 | |||||
| Synonyms |
Fructose-1,6-bisphosphatase isozyme 2; FBPase 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; Muscle FBPase |
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| 3D Structure | ||||||
| Sequence |
MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGI
AGSVNVTGDEVKKLDVLSNSLVINMVQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDP LDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQ GVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAP YGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGS |
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| Target Bioclass |
Enzyme
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| Family |
FBPase class 1 family
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| Subcellular location |
Cell junction
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| Function |
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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Probe 1 Probe Info |
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Y210(21.40) | LDD3495 | [1] | |