Details of the Target

General Information of Target

Target ID LDTP00177
Target Name Short transmembrane mitochondrial protein 1 (STMP1)
Gene Name STMP1
Gene ID 647087
Synonyms
C7orf73; Short transmembrane mitochondrial protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLQFLLGFTLGNVVGMYLAQNYDIPNLAKKLEEIKKDLDAKKKPPSA
Target Bioclass
Other
Family
STMP1 family
Subcellular location
Mitochondrion inner membrane
Function
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly. Required for the formation of mitochondrial supercomplexes (SCs). Also required for the activation of the NLRP3 inflammasome.
Uniprot ID
E0CX11
Ensemble ID
ENST00000507606.3
HGNC ID
HGNC:41909

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K35(10.00); K43(3.39)  LDD0277  [1]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270