Details of the Target
General Information of Target
| Target ID | LDTP00169 | |||||
|---|---|---|---|---|---|---|
| Target Name | Golgi pH regulator A (GPR89A) | |||||
| Gene Name | GPR89A | |||||
| Gene ID | 51463 | |||||
| Synonyms |
GPHRA; GPR89; SH120; Golgi pH regulator A; Protein GPR89A; Putative MAPK-activating protein PM01; Putative NF-kappa-B-activating protein 90 |
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| 3D Structure | ||||||
| Sequence |
MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIF
EILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTF MYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRN VTDTDILALERRLLQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASG SENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWK IFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLL ITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFN FYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP |
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| Target Bioclass |
GPCR
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| Family |
Golgi pH regulator (TC 1.A.38) family
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| Subcellular location |
Golgi apparatus membrane
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| Function |
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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ATP probe Probe Info |
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N.A. | LDD0199 | [1] | |