Details of the Target

General Information of Target

Target ID LDTP00005
Target Name Protein CD300H (CD300H)
Gene Name CD300H
Gene ID 100130520
Synonyms
Protein CD300H; CD300 antigen-like family member H
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTQRAGAAMLPSALLLLCVPGCLTVSGPSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQP
CLPIWHEMVETGGSEGVVRSDQVIITDHPGDLTFTVTLENLTADDAGKYRCGIATILQED
GLSGFLPDPFFQVQVLVSSASSTENSVKTPASPTRPSQCQGSLPSSTCFLLLPLLKVPLL
LSILGAILWVNRPWRTPWTES
Target Bioclass
Other
Family
CD300 family
Subcellular location
Secreted; Membrane
Function May play an important role in innate immunity by mediating a signal for the production of a neutrophil chemoattractant.
Uniprot ID
A0A0K2S4Q6
Ensemble ID
ENST00000641031.1
HGNC ID
HGNC:52292

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2058 SNV: p.E67K .
KYSE510 SNV: p.L14V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0163  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060