General Information of Experiment

Probe Name DBIA  Probe Info 
Probe concentration 500 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
TMT
Competitor Name ARS-1620  Competitor Info 
Competitor Concentration 1 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lung
Disease Model Lung adenocarcinoma [ICD-11:2C25]
Model Name Human lung adenocarcinoma cells (HCC44)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP13062  eIF-2-alpha kinase GCN2 (EIF2AK4) C1255 5.3
 LDTP01827  GTPase KRas (KRAS) C12 4.8

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.