Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name IA-alkyne  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
Isotope tag
Experiment Method
ISO-TOP ABPP
Competitor Name Structure21  Competitor Info 
Competitor Concentration 50 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lymph node
Disease Model Burkitt lymphoma [ICD-11:2A85]
Model Name Human burkitt lymphoma cells (Ramos)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01803  Adenosine deaminase (ADA) 15.3
 LDTP11107  Serine/threonine-protein phosphatase CPPED1 (CPPED1) 14.8
 LDTP01394  DNA fragmentation factor subunit beta (DFFB) 4.3
 LDTP11198  Alanyl-tRNA editing protein Aarsd1 (AARSD1) 4.0

References

1 2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles. J Am Chem Soc. 2020 May 13;142(19):8972-8979. doi: 10.1021/jacs.0c02721. Epub 2020 Apr 29.