General Information of Experiment

Probe Name CHEMBL5092326  Probe Info 
Probe concentration 20 uM
Criteria Other data
Quantitative Method
LFQ
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cell lysate (Hep-G2)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name
 LDTP02576  Pyruvate carboxylase, mitochondrial (PC)

References

1 Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming. J Med Chem. 2022 Jan 13;65(1):460-484. doi: 10.1021/acs.jmedchem.1c01605. Epub 2021 Dec 21.