Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Kambe_24  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name kambe_cp60  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 3.0
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 2.9
 LDTP04134  Retinaldehyde dehydrogenase 3 (ALDH1A3) 2.5
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) 4.1

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.