Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name DBIA  Probe Info 
Probe concentration 500 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
TMT
Experiment Method
SLC ABPP
Competitor Name THZ1  Competitor Info 
Competitor Concentration 5 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Colon
Disease Model Colon carcinoma [ICD-11:2B90]
Model Name Human colon carcinoma cell lysate (HCT 116)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP04379  Cyclin-dependent kinase 7 (CDK7) C312 20.0
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP19407  Immediate early response gene 5-like protein (IER5L) C137 10.0

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.