General Information of Experiment

Probe Name DFG-out-3  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Ranjitkar_cp1  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Skin
Disease Model Skin squamous cell carcinoma [ICD-11:2C31]
Model Name Human skin squamous cell carcinoma cells (A431)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03477  Ephrin type-B receptor 2 (EPHB2) 67.0
 LDTP04629  Ephrin type-B receptor 3 (EPHB3) 32.0
 LDTP03474  Ephrin type-A receptor 2 (EPHA2) 9.4
 LDTP02231  Tyrosine-protein kinase Yes (YES1) 5.5
 LDTP02638  Proto-oncogene tyrosine-protein kinase Src (SRC) 4.1
 LDTP00497  Cyclin-G-associated kinase (GAK) 3.5
 LDTP10201  Atypical kinase COQ8B, mitochondrial (COQ8B) 2.7

References

1 Affinity-based probes based on type II kinase inhibitors. J Am Chem Soc. 2012 Nov 21;134(46):19017-25. doi: 10.1021/ja306035v. Epub 2012 Nov 6.